Treatment There are many forms of monogenic diabetes, and these are due to mutations in different genes. Some can be treated with oral medication, others cannot. Some conditions may be transient. Information on treatment and how, once a genetic diagnosis is made, patients can transfer from insulin is detailed on the Exeter Genetic Diabetes website: www.diabetesgenes.org. In Lilly Jaffe's case, her doctors began by giving her doses of sulfonylurea—a drug developed decades ago to enhance insulin secretion for type 2 patients—and gradually reducing her insulin. Nine days later, she was able to completely stop taking insulin. People with monogenic forms of diabetes still need to check their blood sugar levels, however, they may not need to check as often as a person with type 1 diabetes. For more information about treatment, see the NIH's National Diabetes Information Clearinghouse website.